CIII allows people who have tried at least two oral antidepressants to use the spray on its own – without the need for more ...

The startup's in-house projects include GM-1020, a small-molecule NMDA receptor channel blocker – the mechanism of action for ketamine – which is in phase 2a clinical development for major ...

Novel therapies, particularly those targeting the glutamatergic system, have garnered significant attention. Intravenous ketamine and intranasal S-ketamine are at the forefront of these developments.

Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

Jan. 24, 2025 — The vestibular system is a network of organs in the inner ears that detects the motions and position of the head. The brain uses this information, ... Progress and Challenges in ...

Jan. 13, 2025 — A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show ...

To obtain tissues for experiments, the animals were anesthetized with a mixture of ketamine (100 mg/kg BW) and xylazine (10 mg/kg BW). Mice for light microscopic (LM) analyses were usually fixed by ...